Over-supplementation of calcium in children may lead to an early closure of the fontanelle, but it will not cause microcephaly or affect brain development. The growth of primary teeth is usually related to a reduction of 3 months in the age. If a child does not show obvious signs of calcium deficiency, additional calcium supplementation is not necessary, but they can increase the intake of calcium-rich foods such as milk and soy milk to promote tooth growth. Although an early closure of the fontanelle may be related to calcium supplementation, it will not lead to microcephaly or affect brain development. Parents should not be overly concerned, but they should pay attention to observing their child’s growth and development, and seek medical attention promptly if any abnormalities are detected.