The symptoms of pediatric leukemia include early signs such as laziness, fatigue, decreased appetite, and progressive pallor of the complexion, pain in bones and joints, skin and gum bleeding, among others. In severe cases, there may be enlargement of the liver, spleen, and lymph nodes, systemic failure, and weight loss. If parents notice any suspicious symptoms in their child, they should take the child to the hospital for a routine blood test.