Pediatric benign epilepsy with central temporal lobe spikes is common in children and adolescents aged 3 to 13, often occurring during sleep and presenting as brief, unilateral facial twitches with a tendency to generalize. As the child grows older, the condition usually resolves spontaneously before adolescence, with a good prognosis. The attack usually resolves by the age of 15 to 16, leading to a favorable outcome. The clinical manifestations and seizure characteristics of pediatric benign epilepsy with central temporal lobe spikes have a certain genetic component, with a significantly higher incidence in first-degree relatives. Both limited and generalized increases suggest that the underlying basis of the disease is genetic susceptibility, with increased cortical excitability. This genetic susceptibility often only manifests as pediatric benign epilepsy with central temporal lobe spikes inheritance, with only a small number of patients experiencing typical epilepsy seizures. Parents should be aware of pediatric epilepsy and seek early treatment to avoid long-term suffering in children.