The main symptoms of pinworm disease include anal itching, restless sleep, and gastrointestinal discomfort, among others. In severe cases, symptoms may include restlessness, loss of appetite, pale complexion, and weight loss. At night, when the person is deeply asleep, the pinworms may crawl out from the anus, and they can be found in the feces. The main treatment method is to kill the worms to alleviate itching.