Swelling of the ankles is nephrotic edema caused by kidney disease, which requires attention to low-sodium diet and control of high blood pressure and high blood sugar, with dialysis treatment when necessary.

A 26-year-old patient suddenly developed a fever and leg swelling, was diagnosed with nephritis and hematuria, and underwent five dialysis sessions. Although the cause is unknown, it is said that the patient has congenital renal insufficiency. It is still unclear whether it is acute or chronic renal insufficiency. It is recommended to undergo kidney glomerular filtration rate, 24-hour urine protein quantification, kidney ultrasound, renal artery ultrasound, and other examinations to clarify the condition.