Newborn disease screening through laboratory testing can detect congenital metabolic disorders early, preventing intellectual and physical developmental disabilities, and even death. Gender misidentification does not affect the test results.

Phenylketonuria is a congenital metabolic disorder, primarily treated through dietary therapy. Early detection and treatment yield better outcomes.

PKU children refer to children with phenylketonuria, a congenital metabolic disorder that may affect intelligence and growth and development.