Question

What are the earliest symptoms of hand, foot, and mouth disease?

Answer

The initial symptoms of hand, foot, and mouth disease include low-grade fever, decreased appetite, discomfort, and are often accompanied by sore throat. One to two days after the onset of fever, small blisters appear in the mouth, which then develop into ulcers. Oral ulcers are commonly found on the tongue, gums, and inner mucous membranes of the mouth.