Question

Do O-type RH positive mothers and B-type blood fathers have a risk of hemolytic disease in their second child if the first child had no hemolytic issues?

Answer

According to blood type genetics, there is a risk of newborn ABO hemolytic disease for a combination of O-type RH positive mothers and B-type blood fathers. Regular checks of the mother’s hemolytic antibody titers during pregnancy are necessary to assess the risk. If the antibody titer increases, appropriate preventive measures should be taken, and discussions with doctors about prenatal diagnosis may be necessary. Additionally, postpartum monitoring of the newborn’s hemolytic symptoms should be closely monitored, and timely treatment should be administered.