Question

You are inquiring about the results of a Down syndrome screening at four months of pregnancy, which show a risk rate of 1 in 223 for Down syndrome and 1 in 125,000 for trisomy 18. You would like to know if these are normal circumstances.

Answer

Based on the screening results you provided, the risk rate for Down syndrome is 1 in 223, and the risk rate for trisomy 18 is 1 in 125,000. These numbers indicate a certain level of risk in your situation. It is recommended that you consult with a doctor as soon as possible for further examination to obtain an accurate diagnosis and appropriate treatment advice. Thank you for your inquiry.