Can Couples with Chromosomal Abnormalities Still Have Healthy Babies? What Are the Chances?

Question

Both partners have chromosomal abnormalities. The female partner is 46,XX, and the male partner is 46,XY,21pstk+. They inquire about the possibility of having a healthy baby despite the chromosomal abnormalities and what the success rate might be.

Answer

The examination results show that both partners have chromosomal abnormalities. The female partner is 46,XX, and the male partner is 46,XY,21pstk+. Experts advise against further childbearing due to the extremely high risk of the child having Trisomy 21. Additionally, if the chromosomal issue is responsible, it may be impossible to conceive, and most pregnancies are naturally aborted before week 8.