Analysis of AFPMOM 0.38 in Down Syndrome Screening

Question

What does an AFPMOM (Alpha-fetoprotein Multiple of the Median) test result of 0.38 in Down syndrome screening mean?

Answer

An AFPMOM result of 0.38 indicates that the concentration of alpha-fetoprotein in the maternal plasma is relatively higher than the normal level. This ratio is an important indicator in Down syndrome screening, used to assess the risk of the fetus having Down syndrome or other chromosomal abnormalities. When the AFPMOM ratio is elevated, it may suggest an increased risk of the fetus having Down syndrome or other chromosomal abnormalities. Additionally, it is necessary to combine the risk ratios of trisomy 21 and 18 to comprehensively evaluate the health status of the fetus.