Question

Do chromosomal abnormalities lead to a decrease in progesterone levels?

Answer

There is a close relationship between chromosomal abnormalities and the reduction of progesterone levels. Chromosomal abnormalities are a significant cause of infertility, primarily manifesting as early pregnancy embryo loss and recurrent miscarriage. Studies have shown that approximately 60% of miscarried embryos within the first 12 weeks of pregnancy have chromosomal abnormalities, with the rate significantly decreasing as pregnancy progresses. This suggests that spontaneous abortion caused by chromosomal abnormalities may be a form of natural selection in human evolution. With the development of gene probes and recombinant technologies, the relationship between chromosomal abnormalities and infertility will be further elucidated.