Question

What is the impact of low AFP indicators in Down syndrome screening on infants?

Answer

Generally, low AFP indicators do not have significant pathological significance, but if the concentration of the marker is too low, it may be associated with certain fetal anomalies, such as neural tube defects or kidney malformations. However, a single AFP indicator cannot confirm these conditions; it requires the integration of other screening and diagnostic tools, such as advanced-level ultrasound and amniocentesis. For cases with low AFP indicators, it is recommended to conduct further follow-up checks and closely cooperate with medical professionals to monitor the fetus’s development.