Question

What does the chromosome test report 46xx15p+ mean?

Answer

The chromosome test report shows an individual’s karyotype, with 46xx15p+ indicating that the individual has 46 chromosomes, with an extra segment on one X chromosome. This condition is known as a chromosomal abnormality and may affect an individual’s reproductive function, sexual characteristics, and secondary sexual traits. Specifically:

  1. Individuals with reproductive dysfunction may experience infertility, recurrent miscarriage, and malformed offspring, partly due to chromosomal abnormalities.
  2. Those with abnormal secondary sexual characteristics, such as primary amenorrhea, underdeveloped sexual development, and short stature, may be manifestations of X chromosome abnormalities.
  3. Individuals with ambiguous external genitalia can benefit from chromosomal testing to determine their gender and karyotype.
  4. Children with congenital multiple malformations and intellectual disabilities may suffer from chromosomal diseases such as Trisomy 21.
  5. Individuals with atypical behavior, such as tall stature, aggressive temperament, and aggressive behavior in males, may be manifestations of chromosomal abnormalities such as XYY syndrome. Understanding this information is crucial for diagnosing and treating related diseases.