Question
Can hypogonadism with azoospermia be treated? What is the prognosis?
Answer
The patient was diagnosed with severe oligozoospermia, hyperprolactinemia, hypergonadotropinemia, and hypogonadotropic hypogonadism. It is recommended to continue with a full ultrasound examination of the reproductive system, chromosome microdeletion testing, and seminal fructose and glucosidase tests to rule out causes of testicular damage such as parotitis sequelae, long-term exposure to radiation, high-temperature or heavy metal environments, testicular trauma, cryptorchidism, or inguinal or umbilical hernias. If follicle-stimulating hormone (FSH) levels exceed twice the normal range, the prognosis is typically poor. However, if financial conditions permit, direct in vitro fertilization (IVF) can be considered. For endocrine disorders, bromocriptine plus vitamin B6 can be taken orally, along with a mixed injection of human chorionic gonadotropin (HCG) and human menopausal gonadotropin (HMG), and re-examination after three months.