Question

What are the reasons for excessive sweating, right lower rib pain, and abdominal distension in patients with kidney disease complex syndrome?

Answer

  1. Primary renal disease complex syndrome is more common in children and adolescents, with a male-to-female ratio of about 2:1. Symptoms include general edema with a tendency to be Depression, particularly in the face, lower limbs, and scrotum. There is often ascites, but the overall condition is generally good without hypertension. Urine output is reduced, and urine protein is usually ++~+++++, with a quantitative value >0.1g/(kg·d). Urinalysis occasionally shows a small number of red blood cells. Serum total protein is lower than normal, with a more significant decrease in albumin (＜30g/L). Serum protein electrophoresis shows a decrease in albumin proportion and an increase in globulin proportion, with a decrease in r-globulin. Serum cholesterol is significantly elevated (>5.7mmol/L), and serum complement is normal. Renal function is generally normal, and there may be transient mild azotemia during the edema period with significant oliguria.
  2. Nephritic renal disease complex syndrome usually occurs during the school age period, with the following clinical characteristics: (1) Onset age is more common in children over 7 years old, with mild edema. (2) Blood pressure can be elevated to varying degrees, often with episodic or persistent hypertension and hematuria. (3) Serum complement can be reduced, and there may be varying degrees of azotemia.
  3. Congenital renal disease complex syndrome is rare, mostly an inherited disease with crypto-characteristics, commonly occurring in the neonatal period or within the first three months after birth, presenting similarly to primary renal disease.