Question
A 29-year-old man, after marriage, has a daughter who was found to have developmental abnormalities at birth. The child has congenital malformation, and at the age of 6, still cannot speak or walk. Both parents have been examined, and the husband has a chromosomal abnormality with a karyotype analysis result of: 46,XY, inv(9)(p11q12).
Answer
The situation should be that it is not advisable to have a second child. Individuals with chromosomal abnormalities generally cannot have normal children, and it is recommended not to have children.