Question

Main Symptoms: Onset Time: Laboratory Test Results: Elevated bilirubin levels, high jaundice, and high total bilirubin, significantly high indirect bilirubin.

Answer

The baby needs to be placed in an incubator for blue light therapy, and a blood transfusion may be necessary. Generally, ABO incompatibility hemolytic disease is mild, and most newborns do not require special treatment after birth. Timely blue light therapy and medication can alleviate the condition. Generally, pregnant women are O-type, while the fetus is A-type or B-type, which can lead to neonatal hemolytic disease. ABO incompatibility is more common, accounting for 20% to 25% of total pregnancies, but only 2% to 2.5% develop hemolytic disease, and it is usually mild. This is because the fetus’s tissues contain varying amounts of soluble A or B substances that can neutralize A and B antibodies. Mild ABO hemolytic disease can easily be confused with physiological jaundice in newborns. Some severe cases may progress slowly and reach their peak between the 3rd and 5th day after birth.