Question

What are the symptoms and treatment for Rh incompatibility hemolytic disease in newborns?

Answer

The treatment for neonatal hemolytic disease mainly targets hyperbilirubinemia, aiming to prevent the occurrence of bilirubin encephalopathy. Blood exchange therapy remains the primary method for treating severe hyperbilirubinemia and improving neurotoxicity. It serves three main functions: first, it removes antibody-coated red blood cells and replaces them with red blood cells compatible with the mother, reducing the source of bilirubin production; second, it removes bilirubin from the plasma; third, it removes antibodies that may bind to the infant’s red blood cells.