Question
Main Symptoms: Keratin hard shell on limb areas Onset Time: At birth Laboratory Test Results: Ichthyosis
Answer
Ichthyosis, also known as snake skin disease, is a genetic skin disorder characterized by dry, rough skin with rhombic or polygonal scales, resembling fish scales or snake skin. Currently, there is no cure for the condition, but treatment can alleviate symptoms, increase the water content of the stratum corneum, and promote normal keratinization. Treatment methods include systemic and topical treatments, such as vitamin A, 13-cis retinoic acid, Psorinol, or methotrexate, as well as topical antibiotic ointments. Patients can also use substances to increase the water content of the stratum corneum and remove excessive keratinization, such as urea cream, retinoic acid, salicylic acid, etc. Although “cholecalciferol cream” and “calcipotriol ointment” may be difficult to obtain domestically, these drugs are the latest research findings from Japan and can help control the condition.