Question

What changes can occur if the proteinuria in nephrotic syndrome fails to revert to normal? What problems might arise if one continues to take steroids but the proteinuria remains unchanged?

Answer

Nephrotic syndrome is a condition characterized by significant proteinuria, low albuminemia, hyperlipidemia, and edema. Its typical features include excessive proteinuria, edema, hyperlipidemia, and low plasma protein levels. Severe cases may present with pleural effusion and anuria. Suggested opinion: Proteinuria in nephrotic syndrome is a difficult-to-treat condition caused by kidney damage and protein loss. Various factors or etiologies lead to damage to the glomerular filtration barrier, allowing for the leakage of macromolecular proteins. The key to treatment is to address the fundamental damage or etiology of the kidneys. Once the glomerular basement membrane is repaired, proteins will disappear. Doctor’s question: