Question

A child has recently been diagnosed with metastatic osteosarcoma, experiencing weakness, persistent pain, muscle atrophy, and tumor compression symptoms. How should tests be conducted to confirm the diagnosis?

Answer

The most direct method to diagnose metastatic osteosarcoma is through a biopsy. For a single lesion, it is essential to proceed with direct sampling as soon as possible; for multiple lesions, select areas that are relatively easy to sample for examination.