Question

The patient has been diagnosed with nephrotic syndrome, stage I membranous nephritis, but the treatment response is poor.

Answer

Hello, nephrotic syndrome is one of the common chronic kidney diseases, which is less common in elderly patients. Membranous nephropathy typically presents with a chronic progressive course and recurrent symptoms. It is one of the main factors leading to end-stage renal disease in adults, and renal function impairment often gradually appears 5-10 years after onset. It is particularly important to note that this condition is highly prone to thromboembolic complications, with a high incidence rate of renal vein thrombosis up to 60%. Treatment usually involves hormones, as well as traditional Chinese medicine or integrated Chinese and Western medicine treatments. The aim of nephrotic syndrome treatment is to improve the filtration membrane barrier function of the renal corpuscles, reduce urinary protein, correct pathological and physiological abnormalities, prevent or delay renal fibrosis, protect renal function, and prevent complications and side effects of hormones. If patients have chronic diseases such as hypertension and diabetes, they should be controlled in a timely manner, as these diseases can affect the treatment and recovery of the condition. Patients should also pay attention to adequate rest, avoid overexertion, enhance physical immunity, and prevent colds and other inflammatory diseases. A healthy diet should include low-sodium, low-fat, and high-quality protein (mainly animal protein such as eggs, etc.), supplemented reasonably according to the patient’s protein loss situation. Maintain a positive attitude, and seek timely medical advice for any concerns.