Question
A mother with concerns is a carrier of the hepatitis B virus. Her child was born and received hepatitis B immunoglobulin and vaccine, but only received a booster dose of hepatitis B immunoglobulin on the 31st day, missing the second vaccine dose. Will this affect the effectiveness of the maternal-infant transmission blockade?
Answer
Based on the mother’s description, her primary concern involves the administration of the hepatitis B vaccine. Recommendation: According to individual circumstances, the first dose of hepatitis B immunoglobulin and vaccine should be administered at birth, followed by another vaccine dose one month later, and then a third dose at six months. Alternatively, a single dose of hepatitis B immunoglobulin can be administered at birth, followed by another dose one month later, along with the hepatitis B vaccine. Subsequently, vaccines should be administered separately at one month and six months. According to the description, it seems that the vaccine administration did not proceed as scheduled, which theoretically may affect the generation of hepatitis B antibodies. It is recommended to bring the child to a hospital for a hepatitis B antibody test to determine if antibodies have been generated. If not, vaccination should be administered promptly. Additionally, there are no strict requirements for the injection site, so there is no need to worry excessively.