Question
Is fish scale disease inherited through autosomal chromosomes or sex chromosomes?
Answer
Fish scale disease is a genetic skin disorder characterized by typical symptoms such as dry, gray-brown scales and deep streaks on the skin, with symptoms worsening in winter and improving in summer. Patients usually have no conscious symptoms or only mild itching. If treatment is not timely or the method is inappropriate, the condition may affect the entire body and be inherited to the next generation. The outer sides of the limbs are particularly evident, but the armpits and inner sides of the elbows are usually unaffected. Fish scale disease is hereditary, with about 70-80% of patients having a family history of inheritance. The mode of inheritance varies with the type of disease, mainly including dominant inheritance, recessive inheritance, and codominant inheritance. Dominant inheritance refers to the transmission of traits controlled by dominant genes; recessive inheritance is controlled by recessive genes; and codominant inheritance refers to the simultaneous expression of allelic traits. The genetic mechanism of fish scale disease is not yet fully understood, and its inheritance may be related to environmental factors, diet, and genetic rearrangement mutations in the disease.