Question
A four-year-old girl with nodular sclerosis has been on antiepileptic drugs Tegretol and Clonazepam tablets for a long time, and was later switched to Oxcarbazepine due to poor control. Recently, she has developed symptoms of edema, abdominal distension, and splenomegaly, accompanied by a significant decrease in platelet count. After treatment at a children’s hospital, the edema has subsided, but the spleen remains enlarged, and the platelet count has not improved. Ask about treatment methods to improve the condition.
Answer
Nodular sclerosis is a genetic disease often accompanied by epilepsy and kidney disease changes, which may lead to body edema, splenomegaly, and hyperfunction of the spleen, thus causing thrombocytopenia. Currently, treatment is quite challenging and may require considering splenectomy surgery to improve thrombocytopenia, along with traditional Chinese medicine treatment to increase platelet count, which is hopeful for gradual improvement.