Question
A 5-year-old child has a fever of 38.5 degrees Celsius and the antipyretic effect after taking Mebendazole is not obvious. The child had a fever of 38.5 degrees Celsius last night with no other symptoms. Today, the child went to a large hospital for intravenous drip treatment, including cefalosporin antibiotics and antipyretics. After returning home, the fever rose again to 40 degrees Celsius. How should it be handled?
Answer
Fever occurs due to the release of endogenous substances such as prostaglandins in the body caused by viruses, bacteria, and their metabolic products. These substances act on the thermoregulatory center, leading to a decrease in the set point of temperature regulation. For children with fever, it is generally recommended to use antipyretics when the body temperature exceeds 38.3 degrees Celsius, but in clinical practice, antipyretics are usually given to children when their body temperature exceeds 38 degrees Celsius. You can use compound medications containing ibuprofen or nimesulide for antipyretic purposes, and also prepare pediatric fever-reducing suppositories for use at night to prevent convulsions caused by high fever. During treatment, it may be necessary to use a variety of antibiotics and antipyretic and anti-inflammatory drugs, such as penicillin and cefalosporin antibiotics, as well as ibuprofen and paracetamol. For patients with excessive histamine secretion, antihistamines such as chlorpheniramine may also be needed, as well as pseudoephedrine to alleviate nasal congestion symptoms.