Question
What is the current treatment plan for newborns with congenital adrenal hyperplasia?
Answer
For newborns with congenital adrenal hyperplasia, the current treatment regimen includes taking 2.5 milliliters of hydrocortisone every eight hours and 0.1 grams of fludrocortisone daily. Specific treatment measures include using physiological saline for intravenous fluid replacement in cases of salt-wasting, and using a 0.45% sodium chloride and sodium bicarbonate solution if there is metabolic acidosis. Potassium-containing solutions should be avoided. In severe salt-wasting cases, intravenous infusion of hydrocortisone may be required, and if low sodium and fluid loss are difficult to correct, intramuscular injection of acetate corticosterone (DOCA) or oral fludrocortisone can be administered. After fluid correction, glucocorticoids should be changed to oral administration and maintained long-term, along with oral sodium chloride. The dosage should be adjusted appropriately according to the condition. If there are any discomforts, please visit the hospital for a follow-up consultation.