Question
What does it mean when a child has elevated alanine transaminase?
Answer
Elevated alanine transaminase in children may indicate liver function impairment. It could result from liver cell necrosis or apoptosis, leading to the release of enzymes from liver cells into the bloodstream and a decrease in the liver’s ability to synthesize proteins and glycogen, as well as the retention of metabolic products like bilirubin and ammonia in the blood. Detailed liver function tests and hepatitis B surface antigen tests are recommended, and treatment may involve antibiotics like ciprofloxacin and metronidazole, along with drinking plenty of water and practicing good personal hygiene.