Question

Why would a child before puberty have abnormally high levels of progesterone and estradiol?

Answer

Elevated estradiol levels before puberty may be detected during specific stages of the menstrual cycle, and it is typically only diagnostic when baseline values are measured on the third day of menstruation. Hormone levels vary from individual to individual, with estradiol levels rising with follicle development, and dynamic observation of estradiol levels can help determine the time of ovulation.