Question

How to treat neonatal hemolytic disease when jaundice appears a few hours after birth?

Answer

The key to neonatal treatment at birth is the prevention and treatment of anemia and heart failure. For those with anemia, generalized edema, ascites, and heart failure, after 30-50ml of umbilical vein blood is drawn and abdominal fluid is removed, concentrated blood should be administered immediately. The focus in the first 2 to 7 days after birth is the prevention and treatment of jaundice and bilirubin encephalopathy. Severe anemia should be noted within two months. For the treatment of jaundice and hyperbilirubinemia, phototherapy and traditional Chinese and Western medications can alleviate most cases, but quickly removing antibodies, reducing the continued destruction of red blood cells to lower bilirubin levels, correcting anemia, improving oxygenation, and preventing heart failure still require blood transfusion, which is more effective than phototherapy and medication. However, it requires more manpower and material resources resources and carries risks such as thrombosis, air embolism, cardiac arrest, and infection. Therefore, strict indications should be followed.