Question
How is Juvenile Idiopathic Arthritis caused?
Answer
The causes of Juvenile Idiopathic Arthritis are not entirely clear, but there is a certain genetic predisposition. The primary pathological changes occur in the synovium, which can affect various systems throughout the body. Symptoms include irregular fever, joint pain (especially in small joints), and sometimes accompanied by rashes, enlargement of the liver and spleen, lymph node swelling, myocarditis, and other manifestations. The onset of the disease is not obviously seasonal, but the incidence rate is higher in cold regions. It is more common in children aged 2 to 3 and 9 to 12 years old, with a slightly higher incidence rate in girls than in boys. The disease is prone to chronic recurrence; with proper treatment, it can be relieved into adulthood, but a few may continue to have attacks, and in the late stage, joint deformities may occur, with a very few cases leading to disability.