Question
A 9.5-year-old girl, 1.53 meters tall, has already started menstruating and is inquiring about treatment methods for precocious puberty.
Answer
Treatment for precocious puberty can involve the use of gonadotropin-releasing hormone analogs (GnRHa) or norethindrone acetate. GnRHa can improve final height and is administered by intramuscular injection every 4 weeks, with a dosage of 0.1 to 0.3 milligrams per kilogram. Norethindrone can be taken orally daily for girls with precocious puberty, starting with an initial dose of 10 to 30 milligrams, which can be reduced after efficacy is achieved and maintained.