Question
How to treat newborn sepsis? The baby is male, 15 days old, and was discovered to have umbilical cord infection on November 16, 2005. There are red spots around the umbilical cord, and the bilirubin level started at 290. It was measured at 170 on November 22, and distillation water treatment and blood tests were performed, confirming a bacterial infection. The medication used on November 22 was piperacillin/tazobactam and vitamin C injection. The body temperature is normal at present. Please provide an expert opinion, thank you! Looking forward to your reply!
Answer
Hello, in the case of newborn sepsis, antibiotic treatment should be initiated before obtaining blood culture results. Subsequently, antibiotics should be selected based on the results of the blood culture and bacterial sensitivity testing. Typically, a combination of a penicillin and an aminoglycoside antibiotic is used as the initial choice. This combination has a broad spectrum of antibacterial activity and produces synergistic effects. In severe infection cases, the use of third-generation cephalosporins combined with penicillin is recommended.