Question

What medication is most effective in treating pediatric bronchial asthma? Here is a description of the child’s condition: Repeated coughing attacks, has received treatment at a pediatric hospital in Chongqing, but the results were not very satisfactory. Hope to quickly cure the cough and asthma. Past treatment and effects: During acute attacks, the condition was severe, and high-dose inhaled corticosteroids were used for treatment. Short-term oral prednisone was taken for 1-7 days, 1-2 mg/kg per day (total not exceeding 40 mg), taken in 2-3 doses. For asthma that is corticosteroid-dependent, it can be taken once a day in the morning every other day. However, long-term oral prednisone or dexamethasone may produce adverse reactions, especially greater impact on children who are growing and developing, and should be avoided as much as possible.

Answer

For children with severe (severe) asthma attacks, early intravenous injection treatment should be initiated, commonly used medications include methylprednisolone 1-2 mg/kg or hydrocortisone succinate 5-10 mg/kg, taken twice or thrice daily, generally stopped after 2-5 days of use. If systemic corticosteroids are used for more than 10 days, the dose should be gradually reduced when stopping to avoid symptom recurrence.