Question
At 13 weeks of early pregnancy, the PAPP-A indicator was 6230 mU/L, with a corrected MOM of 1.37. The free-hCG indicator was 81.5 g/mL, with a corrected MOM of 1.88. The NT indicator was 1.2 mm, with a corrected MOM of 0.71. At 16 weeks of mid-pregnancy, the free-hCG indicator decreased to 44.6 g/mL, with a corrected MOM of 2.52. The hAFP indicator was 42.9 U/mL, with a corrected MOM of 1.15, and the uE3 indicator was 4.35 mol/L, with a corrected MOM of 0.92. The risk values for trisomy 21 were 1 in 32,000 and for trisomy 18 were 1 in 10,000, with low-risk NTDs. Are these results normal? What should be done if the free-hCG level is elevated?
Answer
Based on your results, although the free-hCG level is elevated, when considering other indicators (such as PAPP-A, hAFP, uE3, and NT), the risk values for trisomy 21 and trisomy 18 are both within the low-risk range. This suggests that the elevated free-hCG level may be a false-positive result. Typically, Down syndrome screening…