Question
The AFP test shows an OD value of 0.164 and a MoM value of 0.61; the HCG test shows an OD value of 0.838 and a MoM value of 3.77; the risk coefficient for the Down syndrome screening is 1/165 (high risk), with a low-risk reference risk coefficient of less than 1/275. What should one do if the Down syndrome screening result is positive?
Answer
A positive result in the Down syndrome screening indicates a higher likelihood of carrying a child with Down syndrome, placing the pregnant woman in a high-risk category. It is recommended to consult with a relevant clinic for further consultation and diagnosis. Based on the test results, the MoM values for AFP and HCG are within the normal range, but the risk coefficient is high, which may necessitate further procedures such as amniocentesis and fetal chromosome testing to confirm the diagnosis.