Question
Is a hemolysis titer of 1:4 considered normal? Why is a follow-up test needed?
Answer
When the IgG anti-A (B) titer in a pregnant woman’s serum reaches or exceeds 64, there is a possibility of affecting the baby, and enhanced observation is required; when the titer reaches or exceeds 128, the baby is likely to be damaged, and treatment is needed. The purpose of regular follow-up checks is to reduce the antibody titer below 1:64 to minimize the risk of neonatal hemolytic disease.