Question
I experienced a spontaneous abortion at 49 days of pregnancy. In addition to the balanced translocation of chromosomes 3 and 16, all other checks were normal. What treatment should I consider?
Answer
Human cells contain a total of 23 pairs (46 chromosomes), and their quantity and structure are typically fixed. Abnormalities in chromosomes can lead to congenital diseases, such as trisomy 21, which is Down syndrome. Chromosome balanced translocation may reduce fertility, leading to high rates of miscarriage or low pregnancy rates. The solution is to undergo Preimplantation Genetic Diagnosis (PGD), which screens the embryo chromosomes and selects healthy embryos for implantation.