Question

If a man has a low sperm density of less than 2*10^6/ML, almost no A/B-grade sperm, and a chromosomal balance translocation, what treatment should be considered?

Answer

If the male partner has a chromosomal balance translocation, it may increase the risk of early miscarriage and fetal congenital defects. However, due to the large number of sperm in a single ejaculation, and after the natural screening by the female body, the actual miscarriage rate is not very high. It is recommended to try pregnancy again after adjusting both parties’ conditions, and to perform amniocentesis between the 16th to 20th week of pregnancy to exclude any fetal abnormalities.