Question

What are the possible causes of elevated bilirubin in children?

Answer

A 12-year-old female has elevated bilirubin levels with normal transaminases. Ultrasound examination of the liver shows no abnormalities, and there is no blockage in the bile ducts. The tests for hepatitis A, B, and C antibodies are negative.

Possible Causes

  • Drug-induced hepatitis: Taking cold remedies, fever-reducing drugs like Nimesulide, etc., may cause liver damage and elevated bilirubin levels.
  • Other physical conditions: Diarrhea, excessive fatigue, and other conditions can also lead to abnormal liver function.
  • Hemolytic jaundice: If the bilirubin elevation is marked by indirect bilirubin, consider the possibility of hemolytic jaundice.
  • Congenital bilirubin metabolism disorder: There may be congenital bilirubin metabolism disorders.

Treatment Suggestions

  • Rule out medication effects: Based on the medical history, the child only discovered jaundice during the school physical examination and had no other symptoms. It is recommended to first try to rule out the effects of medication.
  • Take Astragalus and Bupleurum Oral Liquid: When bilirubin levels are not significantly elevated, consider taking Astragalus and Bupleurum Oral Liquid as it has a good effect on jaundice reduction.
  • Observation and examination: Observe for hemolytic jaundice or other causes, and further examination at a hospital if necessary.