Question
Is G6PD deficiency genetic? Are there other factors or causes that can lead to this disease? Is this disease only preventable? Can it be treated? Does blood testing during neonatal jaundice affect this result?
Answer
A lack of glucose-6-phosphate dehydrogenase (G6PD) in red blood cells is known as G6PD deficiency, also commonly referred to as sickle cell anemia. This is a genetic disorder that is widespread in the provinces of South China and Southwest China. Up to 5-10% of people in Guangdong Province have this disease. The key to managing sickle cell anemia is prevention. Individuals or family members with a history of the disease should avoid eating broad beans and should also avoid contact with broad bean pollen. It is also advisable to avoid using antimalarial drugs like primaquine, antibiotics such as chloramphenicol and sulfonamides, analgesics like aspirin, and common household substances like naphthalene (mothballs).
