Question

When parents are choosing growth hormone treatment for their children, how should they decide between using a water solution or a powder? What are the differences between the two?

Answer

When selecting the administration method for growth hormone, there are differences in the manufacturing processes between short-acting water solutions and short-acting powders. Compared to water solutions, powders may trigger the production of antibodies in the body, which could interfere with the treatment and increase safety risks. However, water solutions have not detected antibodies in the current manufacturing process, so there is no need to worry about antibody issues. Additionally, the use of water solutions with electronic pens is more convenient, helping to reduce children’s fear of injections. Although long-acting water solutions require injection only once a week, the reduced frequency of injections increases the likelihood of missed doses, and long-acting water solutions may pose additional uncertainties.