Question

How should precocious puberty in girls be treated? Which is more effective, traditional Chinese medicine or Western medicine? What medications can be used?

Answer

Precocious puberty refers to the appearance of secondary sexual characteristics before adolescence, such as breast development, the growth of pubic and armpit hair, rapid growth in height and weight, and the development of external genitalia. Treatment methods include using high doses of sex hormones to inhibit the secretion of hypothalamic-pituitary gonadotropin. Medroxyprogesterone acetate (also known as medroxyprogesterone) is one such medication, taken orally at a daily dose of 10 to 30 milligrams, which can be increased after seeing results to maintain efficacy. Cyproterone acetate, a derivative of 17-hydroxyprogesterone, not only blocks sex hormone receptors but also reduces the release of gonadotropins, with a daily dose of 70 to 150 milligrams per square meter. These medications may not stabilize adult height.