Question
The risk of Down syndrome is 1 in 812, the risk of trisomy 18 is 1 in 4,232, and the risk of an open neural tube defect is 1.07. Are these values normal? Do I need to undergo non-invasive DNA testing?
Answer
Down syndrome can have a significant impact on a child’s health, and timely and accurate treatment is crucial for the child’s well-being. Prenatal screening can be done by testing the concentration of alpha-fetoprotein (AFP), human chorionic gonadotropin (β-hCG), unconjugated estriol (uE3), and inhibin A in the blood, combined with the age of the pregnant woman, to calculate the risk of carrying a fetus with Down syndrome. It is recommended to consult a professional physician to decide whether to undergo non-invasive DNA testing or other further examinations based on individual circumstances.