Question
Can childhood-suppressive medications for precocious puberty cure children’s early maturity? What medications are used to suppress childhood precocious puberty?
Answer
Currently, the most effective medication for treating true precocious puberty is gonadotropin-releasing hormone (GnRH) analogs. These drugs increase the secretion of gonadotropins and reduce their biological activity, thereby delaying the onset of puberty. However, these drugs are typically used for more severe cases of precocious puberty, usually when entering the fifth or sixth stage of puberty or at the onset of menstruation. These medications are not suitable for false precocious puberty.