Question

Hand, Foot, and Mouth Disease Symptoms in Children

Answer

Acute onset with fever; scattered blisters on the oral mucosa, the size of grains of rice, with significant pain; blisters on the palms or soles of the hands and feet, occasionally visible on the buttocks or knees. The blisters have inflammatory redness around them and contain less fluid. Some children may also experience symptoms such as coughing, runny nose, loss of appetite, nausea, dry heaves, and headache. The disease is self-limiting with a good prognosis and no sequelae. In very rare cases, some children may develop severe complications such as meningitis, encephalitis, myocarditis, flaccid paralysis, and pulmonary edema.