Question
After two years of divorce, I have no children. Four years ago, I had a miscarriage, and last year, I had an ectopic pregnancy. After detailed examination, it was found that my chromosomes are 46yxx, lah+, inv(9)1. What kind of chromosome abnormality is this? How should I deal with it? If I want to have a child, what should I do?
Answer
Chromosomes are carriers of genetic material, the form in which deoxyribonucleic acid (DNA) and nuclear proteins are expressed during cell division. Normal human cells have 46 chromosomes, with a certain shape and structure. Abnormalities in chromosome shape or number are called chromosomal abnormalities, and diseases caused by chromosomal abnormalities are known as chromosomal diseases. More than 100 different types of chromosomal diseases have been discovered so far. Clinically, chromosomal diseases often lead to miscarriage, congenital mental retardation, congenital multiple malformations, and cancer.