What Does a 21st Chromosome Abnormality Mean?

Question

My karyotype is 45xxrob(1321), and the FISH report shows a count of 112 cells. It was found that 100 cells with abnormal 21st chromosome signals, accounting for 89.3% of the total, what does this mean?

Answer

Based on your description and the test report, it is recommended that you consult a genetic transmission across generations clinic to obtain professional opinions and guidance. Chromosome abnormalities require a systematic analysis by doctors at the genetic transmission across generations clinic, including how they may affect fertility and the possible occurrence rates.