Question
What are the characteristics of chromosomal disorders?
Answer
The first point is an abnormal number of chromosomes (the normal number is 46, with males being 46,XY and females 46,XX). There are anomalies such as the reappearance of 45 and 47 chromosomes, as well as variations in trisomies and tetrasomies. In addition to structural abnormalities caused by viruses, such as chromosomal abnormalities, deletions, and translocations, any number or minor structural abnormalities in chromosomes can lead to the enhancement or deletion of many genes, resulting in a variety of different deformities. Chromosomal abnormalities are a fundamental factor in congenital malformations, cases of children with intellectual disabilities of unknown cause, delayed development at birth, and miscarriage.